Buy 3-MeO-PCP Online – Premium Research Chemical
Introduction to 3-MeO-PCP
3-Methoxyphencyclidine, commonly known as 3-MeO-PCP, is a synthetic dissociative anesthetic belonging to the arylcyclohexylamine class . First synthesized in 1979 by Parke-Davis to investigate the structure-activity relationship of phencyclidine derivatives , this compound has become a subject of research interest in recent years.
When you buy 3-MeO-PCP online for research purposes, you are acquiring a compound that acts as a non-competitive antagonist of glutamate N-methyl-D-aspartate (NMDA) receptors . It binds to the NMDA receptor with higher affinity than phencyclidine (PCP) .
Understanding the Regulatory Status
3-MeO-PCP is a Schedule I controlled substance in the United States as of April 22, 2026 . The DEA has permanently placed 3-MeO-PCP in Schedule I of the Controlled Substances Act to fulfill the United States’ obligations under the 1971 Convention on Psychotropic Substances .
Key Regulatory Information:
- DEA Schedule: Schedule I (USA)
- CAS Number: 72242-03-6 (base), 91164-58-8 (hydrochloride)
- Molecular Formula: C₁₈H₂₇NO
- Molecular Weight: 273.42 g/mol
In Canada: 3-MeO-PCP is classified as a Schedule I substance under the Controlled Drugs and Substances Act .
In the UK: 3-MeO-PCP is a Class B controlled substance .
Research Applications
3-MeO-PCP has been the subject of scientific investigation due to its pharmacological properties:
Mechanism of Action
3-MeO-PCP is a non-competitive antagonist of glutamate NMDA receptors, producing dissociative anesthetic and hallucinogenic effects similar to phencyclidine . It binds to the NMDA receptor with a Ki of 20 nM and has affinity for the serotonin transporter (Ki: 216 nM) and sigma1 receptor (Ki: 42) .
Pharmacokinetics
In silico studies have characterized the ADME profile of 3-MeO-PCP . Key findings include:
- High passive permeability and high gastrointestinal absorption
- Blood-brain barrier access
- High plasma protein binding (~70-80%)
- Metabolic liability: Primarily CYP3A4, CYP2D6 and CYP2C19, with early O-demethylation to phenolic metabolites followed by rapid glucuronidation
Toxicology Research
Computational toxicology studies have highlighted the importance of understanding the risks associated with PCP-type substances . These studies confirm that PCP-type substances should be considered compounds of high toxicological concern.
Why Choose a Research-Grade Supplier?
When you buy 3-MeO-PCP online for research purposes, choose a supplier that provides:
Quality Assurance
Products are typically available in research-grade purity. 3-MeO-PCP hydrochloride appears as a white crystalline solid with a melting point of 204-205°C . Research-grade suppliers offer products for legitimate forensic, clinical, toxicological, pharmaceutical, and academic research.
Secure Ordering
Legitimate suppliers offer secure ordering processes for qualified researchers. Orders are confirmed upon receiving official requests, and payment terms can be arranged for established customers .
Frequently Asked Questions
Q: What is 3-MeO-PCP?
A: 3-MeO-PCP is a synthetic dissociative anesthetic drug belonging to the arylcyclohexylamine class. It is a 3-methoxy derivative of phencyclidine (PCP) and acts as a non-competitive NMDA receptor antagonist .
Q: Is 3-MeO-PCP legal?
A: 3-MeO-PCP is a Schedule I controlled substance in the United States . It is also controlled in Canada (Schedule I) and the UK (Class B) .
Q: What is the CAS number for 3-MeO-PCP?
A: 72242-03-6 (base) and 91164-58-8 (hydrochloride) .
Q: What are the research applications of 3-MeO-PCP?
A: Research applications include NMDA receptor pharmacology, structure-activity relationship studies, forensic toxicology, and analytical method development .
Q: How should 3-MeO-PCP be stored?
A: Store in a cool, dark, dry place at -20°C, protected from light and moisture.
Legal Disclaimer: This product is intended for research and analytical purposes only. 3-MeO-PCP is a Schedule I controlled substance in the United States . Customers must possess all required licenses, permits, and authorizations under applicable controlled substances legislation. The DEA has determined that 3-MeO-PCP has a high potential for abuse, no currently accepted medical use in the United States, and lacks accepted safety for use under medical supervision . This product is offered exclusively for legitimate research purposes. Must be 21+ to purchase. Ensure compliance with all applicable laws and regulations in your jurisdiction.