JWH-073 (naphthalen-1-yl-(1-butylindol-3-yl)methanone) is a synthetic cannabinoid receptor agonist from the naphthoylindole family that has been extensively studied for its affinity and activity at cannabinoid CB1 and CB2 receptors . Named after Professor John W. Huffman, the researcher who pioneered this class of compounds, JWH-073 represents a significant research chemical for cannabinoid pharmacology studies.

When you buy JWH-073 online from Colorado Shroom Store, you gain access to a premium quality research compound that meets rigorous analytical standards. The chemical is structurally characterized with a CAS number 208987-48-8, molecular formula C₂₃H₂₁NO, and molecular weight 327.42 g/mol . Our high purity JWH-073 powder is sourced from reputable manufacturers and verified through independent laboratory testing .

JWH-073 is recognized as a mildly selective agonist at CB1 and CB2 receptors, with Ki values of 8.9 nM for CB1 binding and 38 nM for CB2 binding . This distinct pharmacological profile makes JWH-073 valuable for receptor-specific pathway dissection and pharmacological research. Research has shown that JWH-073 produces behavioral effects very similar to Delta-9-THC and has been identified in various “herbal blend” products .

Researchers choose to purchase JWH-073 for a variety of scientific investigations, including:

• Cannabinoid receptor binding and functional studies

• Structure-activity relationship (SAR) investigations of synthetic cannabinoids

• Analytical chemistry method development and validation

• Forensic and toxicological research for New Psychoactive Substance (NPS) detection

• Development of detection methods for synthetic cannabinoids in biological matrices 

When you order JWH-073 USA, you are investing in a research chemical that has been carefully characterized and documented. JWH-073 has been found as a recreational drug in Spice products and is a controlled substance in the USA . Our JWH-073 powder is tested for purity exceeding 98%, with certificates of analysis available upon request .

H2: Understanding the Research Chemical Category

Research chemicals are specialized synthetic substances created exclusively for scientific and laboratory investigations. These compounds are not approved for human consumption or therapeutic use; they are solely intended for usage in controlled laboratory environments. Research chemicals may include novel compounds, analogs of existing drugs, or substances specifically designed to study biological processes and molecular interactions.

At Colorado Shroom Store, we provide premium quality research chemicals to support the scientific community. As a trusted research chemical supplier, we understand the critical importance of product purity, consistency, and reliability in research applications. When you buy research chemicals online from us, you benefit from:

• Lab-tested products with certificates of analysis

• Secure checkout for protected transactions

• Fast shipping with discreet packaging

• Competitive pricing with bulk discounts available

Key Applications of Research Chemicals:

• Drug Discovery: Research chemicals play a key role in generating lead compounds and evaluating their potential in preclinical studies, including high-throughput screening, hit-to-lead optimization, and structure-activity relationship (SAR) studies.

• Target Identification and Validation: These substances help researchers explore novel drug targets, validate therapeutic hypotheses, and identify disease-specific biomarkers.

• Preclinical Evaluation: Research chemicals are essential for assessing pharmacokinetics, pharmacodynamics, safety profiles, and toxicity in in vivo studies.

• Analytical Method Development: Scientists use these compounds to develop and validate detection methods for forensic and toxicological applications.

 Understanding JWH-073 Scientific Background

Chemical Identity and Properties

JWH-073 is a naphthoylindole synthetic cannabinoid with the systematic name (1-butyl-1H-indol-3-yl)-1-naphthalenyl-methanone . The compound has a CAS number 208987-48-8 and is classified as a DEA Schedule I substance . Its molecular formula is C₂₃H₂₁NO, with a molecular weight of 327.42 g/mol . The compound is classified as an analytical standard with a purity of ≥97% .

Receptor Pharmacology

JWH-073 is a mildly selective agonist at the CB1 and CB2 cannabinoid receptors . Research has demonstrated that JWH-073 binds to CB1 receptors with a Ki of 8.9 nM and to CB2 receptors with a Ki of 38 nM, representing a CB1:CB2 ratio of 0.23 . It acts as a neutral antagonist of CB1 cannabinoid receptor and binder of CB2 cannabinoid receptor . Its effects on suppression of spontaneous activity, antinociceptive effect in the tail-flick assay, and rectal temperature are comparable to those of WIN 55,212-2 when tested in rats .

Metabolism and Pharmacokinetics

JWH-073 is extensively metabolized prior to excretion and, as a result, present at very low levels in urine samples. Its metabolites are better targets for assays . Hydroxylated metabolites of JWH-073 have been identified, with the monohydroxylated form being the predominant metabolite in human urine . JWH-073 shares oxidative metabolite patterns with JWH-018, and metabolites are excreted as glucuronide conjugates . UGT1A1, UGT1A3, UGT1A9, UGT1A10, and UGT2B7 have been identified as the major enzymes involved in glucuronidation of hydroxylated metabolites .

Behavioral Pharmacology Studies

Research has shown that JWH-073 produces behavioral effects very similar to Delta-9-THC . In animal studies, acute administration of JWH-073 transiently decreased motor activity for up to 25 minutes and altered memory function for up to 24 hours . EEG studies revealed significant changes in brain electrical activity in both the somatosensory cortex and hippocampus . In vitro results support cognitive function impairment by interfering with hippocampal synaptic transmission and Long-Term Potentiation (LTP) generation .

In drug discrimination studies in rhesus monkeys, JWH-073 fully substituted for the discriminative stimulus effects of Δ9-THC, with an ED₅₀ value of 0.058 mg/kg . The duration of action of JWH-073 was approximately 1 hour, compared to 2 hours for JWH-018 and 4 hours for Δ9-THC . The relatively short duration of action of JWH-073 might lead to more frequent use, strengthening habitual use .

Research Applications

• Behavioural Pharmacology: The cannabinoid tetrad assay (catalepsy, hypothermia, analgesia, and suppressed locomotor activity) is widely used to characterize the behavioural effects of CB1 receptor agonists. JWH-073 has been shown to induce marked hypothermia, increase pain threshold, cause catalepsy, reduce motor activity, and impair sensorimotor responses in animal models .

• Forensic and Analytical Chemistry: JWH-073 and its metabolites can be detected and quantified in biological matrices using GC-MS and LC-MS/MS . Analytical standards are available for method development and forensic applications.

• Structure-Activity Relationships (SAR): Studies have examined the influence of the N-1 alkyl chain length of cannabimimetic indoles upon CB1 and CB2 receptor binding . The butyl homologue of JWH-018 appears to bind to CB1 receptors more specifically .

 Why Quality Matters When You Buy JWH-073

When you buy JWH-073 online, understanding the importance of product quality is essential for successful research outcomes. Research is only as reliable as the compounds you use. JWH-073 is a synthetic compound requiring careful synthesis and purification to ensure consistent results.

Key Quality Indicators:

• Purity: Our ≥97% purity ensures minimal interference in research protocols 

• Consistency: Batch-to-batch consistency ensures reproducible results

• Verification: Independent laboratory testing validates product integrity

• Storage: Proper handling and storage conditions maintained throughout distribution

 Why Choose Colorado Shroom Store?

As a trusted supplier of premium research chemicals, Colorado Shroom Store sets the standard for quality, reliability, and customer service. When you buy JWH-073 online from us, you benefit from:

Premium Quality Products
Our JWH-073 for sale undergoes comprehensive laboratory testing with certificates of analysis available upon request. We source from reputable manufacturers and verify purity through independent analysis. Our product is ≥97% pure, suitable for research applications .

Authentic & Verified Compounds
Every batch of our JWH073 is accompanied by detailed product specifications, ensuring you receive the exact compound you ordered. The correct CAS number is 208987-48-8 .

Secure Checkout Experience
Our platform features secure checkout with multiple payment options, protecting your information throughout the transaction.

Discreet USA & Canada Delivery
We prioritize your privacy with discreet shipping and camouflage packaging for all orders. Fast shipping is available to all 50 states and Canadian provinces.

Competitive Pricing & Bulk Discounts
Whether you need a single unit or wholesale quantities, our pricing structure rewards larger orders. Buy JWH-073 in bulk and save on your research chemical needs.

Excellent Customer Support
Our knowledgeable team understands the technical requirements of research chemicals and is available to assist with your questions.

 Buy JWH-073 Cheap and Safe Colorado

When you buy JWH-073 cheap and safe Colorado, Colorado Shroom Store is your trusted local source for premium research chemicals. We understand that researchers need reliable access to quality compounds at competitive prices. Our Colorado-based operations allow us to provide:

• Competitive pricing without compromising quality

• Fast shipping to all Colorado locations

• Local customer support in your time zone

• Secure transactions with multiple payment options

• Discreet packaging delivered directly to your laboratory or research facility

 The Importance of Buying JWH-073 from a Trusted Source

Purchasing JWH-073 from a reputable supplier is of paramount importance for several reasons:

1. Product Integrity and Purity
JWH-073 is a research chemical that requires careful synthesis and purification. The presence of impurities or incorrect isomers can compromise research results. Our lab-tested JWH-073 is verified to ≥97% purity, ensuring accurate and reproducible experimental outcomes .

2. Regulatory Compliance
JWH-073 is regulated as a Schedule I controlled substance in the United States . It is controlled in numerous jurisdictions worldwide . Purchasing from a legitimate supplier ensures compliance with applicable regulations. The DEA has used emergency scheduling authority to control JWH-073 and other synthetic cannabinoids .

3. Forensic and Research Legitimacy
For forensic and analytical research, traceability and documentation are essential. Our JWH-073 is supplied with Certificates of Analysis confirming identity and purity, meeting the requirements of analytical laboratories.

4. Safety Considerations
JWH-073 has been associated with significant effects in scientific studies. Research demonstrates that JWH-073, administered separately, induced marked hypothermia, increased pain threshold to noxious stimuli, caused catalepsy, reduced motor activity, impaired sensorimotor responses, caused seizures, myoclonia, hyperreflexia, and promoted aggressiveness in animal models . Co-administration of ineffective doses of JWH-073 with other synthetic cannabinoids potentiated the detrimental effects, suggesting synergistic action that may increase dangerousness and abuse potential . Users have misrepresented JWH-073 as a “safe JWH-018 alternative,” but research indicates it poses a significant threat to consumers . These findings underscore the importance of handling JWH-073 only in controlled laboratory settings with appropriate safety protocols.

 Explore Our JWH-073 Selection

Our JWH-073 research chemical is available in a high purity crystalline powder form. When you buy JWH-073 USA, you receive:

Product Specifications

• Chemical Name: 1-Butyl-3-(1-naphthoyl)indole / (1-butyl-1H-indol-3-yl)(naphthalen-1-yl)methanone

• CAS Number: 208987-48-8 

• Molecular Formula: C₂₃H₂₁NO 

• Molecular Weight: 327.42 g/mol 

• Appearance: White to off-white crystalline solid 

• Purity: ≥97% (lab-tested) 

• Solubility: DMF: 20 mg/ml, DMSO: 10 mg/ml, Ethanol: 20 mg/ml, Methanol: 10 mg/ml 

• λmax: 218, 316 nm 

• Storage: Store at -20°C, protect from light 

• Shipping: Room temperature in continental US; stability ≥5 years 

• Regulatory Status: DEA Schedule I 

Available Quantities

• Single-unit purchases for individual researchers

• Bulk quantities for laboratories and institutions

• Wholesale pricing for commercial research organizations

 How to Store Research Chemicals Correctly

Proper chemical storage is essential for maintaining compound integrity, ensuring safety, and maximizing efficiency in the laboratory. Good chemical and sample management helps you avoid repeating experiments, save costs, and avoid costly waste disposal of expired chemicals.

General Storage Guidelines:

Containers

• Chemicals must be stored in containers made of material compatible with the chemical

• Containers must be in good condition with no signs of cracks or corrosion

• Containers must have lids that can be closed tightly to prevent evaporation and leakage, even if the container falls over

• Ensure all containers are clearly labeled with the chemical’s full name, CAS number, owner’s name, date of receipt, and any necessary hazard information

Segregation by Compatibility

• Incompatible chemical classes must be segregated by cabinets, distance, and/or secondary containment

• Separate acids from bases, cyanides, azides, bleach, sulfides, and metals

• Store oxidizers away from organics and reducing agents

• Store organics and inorganics separately

• Separate pyrophoric materials from flammables

• Do not store chemicals alphabetically – always store by compatibility

Temperature Control

• Many research chemicals require cold storage at -20°C to preserve stability

• For compounds like JWH-073, storage at -20°C is recommended with stability of ≥5 years 

• Do not store flammable liquids or volatile hazardous chemicals in cold or warm rooms

• Flammable-material storage refrigerators are mandatory for cold storage of flammable chemicals

Recommended Storage Conditions by Chemical Type:

Best Practices:

• Store chemicals on sturdy, level shelving with liquid chemicals not stored above eye level

• Do not store chemicals on the floor unless in secondary containment

• Return chemicals to their designated storage promptly after use

• Schedule regular inventories and remove expired chemicals

• If incompatible materials must be stored in the same cabinet, provide secondary containment and segregation

• Use desiccators for chemicals that react with air or water or are hygroscopic

 Bulk Orders – Wholesale JWH-073 for Research Institutions

For research institutions, contract research organizations, and commercial laboratories, Colorado Shroom Store offers bulk JWH-073 at competitive wholesale prices. Buy JWH-073 in bulk and enjoy significant savings on large orders.

Benefits of Bulk Ordering:

• Volume Discounts: Tiered pricing rewards larger quantities

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• Consistent Supply: Ensure uninterrupted research with reliable inventory

Contact our team to discuss your JWH-073 wholesale requirements and receive a customized quote.

 Delivery Information – USA & Canada Shipping

Colorado Shroom Store is committed to providing reliable, discreet shipping for all research chemical orders. When you buy JWH-073 online from us, you can expect:

USA Delivery

• Fast shipping to all 50 states

• Tracking number provided for all orders

• Discreet packaging ensuring your privacy

• Overnight delivery options available for urgent research needs

• Room temperature shipping in continental US; stability ≥5 years 

Canada Delivery

• Secure delivery to all Canadian provinces

• Compliance with Canadian import regulations

• Camouflage packaging for discretion

• Real-time tracking information

• Fast shipping to major Canadian cities

Shipping Security

• Vacuum-sealed and odor-proof packaging

• Insurance options for shipment protection

• Signature confirmation for high-value orders

 Why Customers Choose Colorado Shroom Store

Our customers consistently choose Colorado Shroom Store for their research chemical needs because we deliver on our promises of quality, reliability, and service.

Trust & Reliability

• Years of experience in the research chemical industry

• Established relationships with reputable manufacturers

• Consistent product quality verified through independent testing

Customer-Centric Service

• Knowledgeable support team with technical expertise

• Responsive customer service during business hours

• Commitment to customer satisfaction

Shopping Experience

• Easy online ordering with secure checkout

• Transparent product specifications and pricing

• Comprehensive product information to inform purchasing decisions

Frequently Asked Questions (FAQs)

Q: What is JWH-073?
A: JWH-073 is a synthetic cannabinoid receptor agonist from the naphthoylindole family, also known as (1-butyl-1H-indol-3-yl)(naphthalen-1-yl)methanone. It acts as a cannabinoid agonist at both the CB1 and CB2 receptors and is used for research purposes .

Q: What is the CAS number for JWH-073?
A: The CAS number for JWH-073 is 208987-48-8 .

Q: What is the purity of your JWH-073?
A: Our JWH-073 is lab-tested and meets rigorous quality standards with ≥97% purity . Certificate of analysis is available upon request.

Q: How should I store JWH-073?
A: Store in a well-closed container at -20°C in a cool, dry place, protected from light and moisture. Stability is ≥5 years under proper storage conditions .

Q: What are the physical properties of JWH-073?
A: JWH-073 has a molecular formula of C₂₃H₂₁NO and a molecular weight of 327.42 g/mol. It appears as a white to off-white crystalline solid with λmax at 218 and 316 nm . Solubility: DMF (20 mg/ml), DMSO (10 mg/ml), Ethanol (20 mg/ml), Methanol (10 mg/ml) .

Q: Is JWH-073 legal to purchase?
A: JWH-073 is a Schedule I controlled substance in the United States and is controlled in numerous jurisdictions worldwide . It is intended for research and forensic applications only. Please ensure compliance with all applicable laws in your jurisdiction.

Q: What is the mechanism of action of JWH-073?
A: JWH-073 acts as a mildly selective agonist at CB1 and CB2 cannabinoid receptors. It has Ki values of 8.9 nM for CB1 binding and 38 nM for CB2 binding .

Q: What are the research applications of JWH-073?
A: JWH-073 is used in cannabinoid receptor binding and functional studies, structure-activity relationship investigations, analytical method development, and forensic and toxicological research .

Q: What payment methods do you accept?
A: We offer multiple secure checkout options. Buy JWH-073 with credit card or choose from other secure payment methods.

Q: Do you offer USA delivery?
A: Yes, we provide reliable USA delivery to all 50 states with fast shipping options.

Q: Do you offer Canada delivery?
A: Yes, we provide dependable Canada delivery with tracking and discreet packaging.

Q: Can I buy JWH-073 in bulk?
A: Yes, we offer bulk sales and wholesale pricing for qualified buyers. Buy JWH-073 in bulk and save. Contact us for a quote.

Q: Is your shipping discreet?
A: Yes, we use discreet packaging and camouflage methods to ensure your privacy. We offer fast shipping with tracking for all orders.

Q: Do you offer overnight shipping?
A: Yes, overnight shipping is available for qualifying orders. Buy JWH-073 with fast shipping and receive your order quickly.

Q: What are the behavioral effects of JWH-073 in research?
A: Research demonstrates that JWH-073 induces marked hypothermia, increased pain threshold, catalepsy, reduced motor activity, impaired sensorimotor responses, seizures, myoclonia, hyperreflexia, and aggressiveness in animal models. Co-administration with other synthetic cannabinoids may potentiate these effects .

Q: What is the duration of action of JWH-073?
A: In drug discrimination studies in rhesus monkeys, the duration of action of JWH-073 was approximately 1 hour, compared to 2 hours for JWH-018 and 4 hours for Δ9-THC .

Q: What are the metabolites of JWH-073?
A: JWH-073 is extensively metabolized, with the monohydroxylated form being the predominant metabolite in human urine. Hydroxylated metabolites are excreted as glucuronide conjugates. JWH-073 shares oxidative metabolite patterns with JWH-018 .

Q: Is a Certificate of Analysis (COA) provided with my order?
A: Yes, every order comes with a Certificate of Analysis confirming the identity and purity of the product.

Q: Can I use JWH-073 for human consumption?
A: No. This product is intended for research and laboratory applications only. It is not for human or veterinary use .

Q: What are the synonyms for JWH-073?
A: JWH-073 is also known as 1-butyl-3-(1-naphthoyl)indole, DEA No. 7173, (1-butyl-1H-indol-3-yl)(naphthalen-1-yl)methanone, and naphthalen-1-yl-(1-butylindol-3-yl)methanone 

Legal Disclaimer: This product is intended for research and laboratory applications only. It is not for human or veterinary use. JWH-073 is a Schedule I controlled substance in the United States and is controlled in numerous jurisdictions worldwide . This product is intended for research and forensic purposes only. Must be 21+ to purchase. Ensure compliance with all applicable laws and regulations in your jurisdiction