Buy 5-MAPB (5-(2-Methylaminopropyl)benzofuran) Online – Premium Research Chemical

5-(2-Methylaminopropyl)benzofuran, commonly known as 5-MAPB, is a synthetic substituted benzofuran belonging to the aminoalkylbenzofuran class of entactogenic compounds . This research chemical is structurally and pharmacologically related to MDMA and has emerged as a significant compound for scientific investigation due to its unique monoamine releasing properties .

When you buy 5-MAPB online from Colorado Shroom Store, you gain access to a premium quality research compound that meets rigorous analytical standards. 5-MAPB is the N-methylated version of 5-APB and has a CAS number 1823925-53-6 (hydrochloride salt) . Our high purity 5-MAPB powder is sourced from reputable manufacturers and verified through independent laboratory testing, with purity ≥98% .

5-MAPB is recognized as a substrate-type releaser at serotonin (SERT), norepinephrine (NET), and dopamine (DAT) transporters with nanomolar potencies, and acts as a partial agonist at serotonin 5-HT2C receptors . Research has demonstrated that 5-MAPB is approximately 3-fold more potent than MDMA at monoamine transporters . The compound has been shown to strongly increase extracellular serotonin levels in the mouse corpus striatum, with a potency exceeding that of MDMA .

Researchers choose to purchase 5-MAPB for a variety of scientific investigations, including:

• Monoamine transporter release studies at SERT, DAT, and NET

• Structure-activity relationship (SAR) investigations of benzofuran derivatives

• Analytical chemistry method development and validation using LC-MS/MS and GC-MS

• Forensic and toxicological research for New Psychoactive Substance (NPS) detection

• Comparative pharmacology studies with MDMA and other entactogens

When you order 5-MAPB USA, you are investing in a research chemical that has been carefully characterized and documented. 5-MAPB has been found in seized samples suspected of containing novel psychoactive substances (NPS) . Our 5-MAPB powder is tested for purity exceeding 98%, with certificates of analysis available upon request.

 Understanding the Research Chemical Category

Research chemicals are specialized synthetic substances created exclusively for scientific and laboratory investigations. These compounds are not approved for human consumption or therapeutic use; they are solely intended for usage in controlled laboratory environments. Research chemicals may include novel compounds, analogs of existing drugs, or substances specifically designed to study biological processes and molecular interactions.

At Colorado Shroom Store, we provide premium quality research chemicals to support the scientific community. As a trusted research chemical supplier, we understand the critical importance of product purity, consistency, and reliability in research applications. When you buy research chemicals online from us, you benefit from:

• Lab-tested products with certificates of analysis

• Secure checkout for protected transactions

• Fast shipping with discreet packaging

• Competitive pricing with bulk discounts available

Key Applications of Research Chemicals:

• Drug Discovery: Research chemicals play a key role in generating lead compounds and evaluating their potential in preclinical studies, including high-throughput screening, hit-to-lead optimization, and structure-activity relationship (SAR) studies.

• Target Identification and Validation: These substances help researchers explore novel drug targets, validate therapeutic hypotheses, and identify disease-specific biomarkers.

• Preclinical Evaluation: Research chemicals are essential for assessing pharmacokinetics, pharmacodynamics, safety profiles, and toxicity in in vivo studies.

• Analytical Method Development: Scientists use these compounds to develop and validate detection methods for forensic and toxicological applications.

H2: Understanding 5-MAPB Scientific Background

Chemical Identity and Properties

5-MAPB is a substituted benzofuran with the formal name N,α-dimethyl-5-benzofuranethanamine, monohydrochloride . The compound has a molecular formula of C₁₂H₁₅NO·HCl and a formula weight of 225.7 g/mol . It appears as a white to off-white crystalline solid . The CAS number is 1823925-53-6 .

Key Physical Properties:

• Molecular Formula: C₁₂H₁₅NO·HCl

• Molecular Weight: 225.7 g/mol

• Purity: ≥98%

• Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml

• λmax: 246, 279, 286 nm

• Storage: Store at -20°C, protect from light

• Shipping: Room temperature in continental US

Receptor Pharmacology

5-MAPB functions as a substrate-type releaser at monoamine transporters, with the following potency profile:

Comparative Potency:

• 5-MAPB is approximately 1.3-fold more potent than MDMA at SERT (MDMA EC₅₀ = 85 nM)

• 5-MAPB is approximately 2.9-fold more potent than MDMA at DAT (MDMA EC₅₀ = 120 nM)

• 5-MAPB is approximately 3.8-fold more potent than MDMA at NET (MDMA EC₅₀ = 90 nM)

5-HT2 Receptor Profile:

5-MAPB’s 5-HT2 receptor agonism is restricted to the 5-HT2C subtype, unlike 5-APB which displays broad 5-HT2A/B/C agonist activity . Additionally, 5-MAPB has been identified as a potent agonist of the serotonin 5-HT1B receptor .

Metabolism and Pharmacokinetics

The main metabolites of 5-MAPB are:

• 5-APB (N-demethyl metabolite)

• 3-carboxymethyl-4-hydroxy methamphetamine

The cytochrome P450 (CYP) isoenzymes involved in 5-MAPB N-demethylation are CYP1A2, CYP2B6, CYP2C19, and CYP2D6, with CYP2B6 responsible for the main part of the total CYP-dependent clearance . Unlike MDMA and MDA, 5-MAPB does not generate the α-methyldopamine neurotoxic metabolite .

In forensic case reports, plasma concentrations of 5-MAPB ranged from 5 to 124 μg/L, with the N-demethyl metabolite 5-APB ranging from 1 to 38 μg/L . A fatal co-intoxication case reported a postmortem peripheral blood concentration of 101 ng/mL for 5-MAPB .

Safety Considerations

Research has demonstrated that 5-MAPB has a higher risk of lethal intoxication than MDMA. In murine models:

• 5-MAPB (1.6 × 10⁻⁴ mol/kg B.W.) resulted in the death of two-thirds of mice, while the same dose of MDMA caused no deaths

• 5-MAPB produced a 3.41°C ± 0.28°C rise in rectal temperature after 1 hour, compared to 1.85°C ± 0.26°C for MDMA

These findings underscore the importance of handling 5-MAPB only in controlled laboratory settings with appropriate safety protocols.

Research Applications

• Behavioural Pharmacology: In vivo studies demonstrate that 5-MAPB produces MDMA-like discriminative stimulus effects in rats, with all tested compounds producing dose-dependent increases in MDMA-lever responding and full substitution at the highest dose tested .

• Forensic and Analytical Chemistry: 5-MAPB and its metabolites can be detected and quantified in biological matrices using LC-MS/MS and GC-MS. Validated methods are available for clinical and forensic toxicology .

• Neurochemistry: Microdialysis studies show that 5-MAPB strongly increases extracellular serotonin, dopamine, and norepinephrine levels in the mouse striatum, with a potency exceeding that of MDMA .

Why Quality Matters When You Buy 5-MAPB

When you buy 5-MAPB online, understanding the importance of product quality is essential for successful research outcomes. Research is only as reliable as the compounds you use. 5-MAPB is a synthetic compound requiring careful synthesis and purification to ensure consistent results. The presence of impurities or incorrect isomers can compromise research results.

Key Quality Indicators:

• Purity: Our ≥98% purity ensures minimal interference in research protocols

• Consistency: Batch-to-batch consistency ensures reproducible results

• Verification: Independent laboratory testing validates product integrity

• Storage: Proper handling and storage conditions maintained throughout distribution

Why Choose Colorado Shroom Store?

As a trusted supplier of premium research chemicals, Colorado Shroom Store sets the standard for quality, reliability, and customer service. When you buy 5-MAPB online from us, you benefit from:

Premium Quality Products
Our 5-MAPB for sale undergoes comprehensive laboratory testing with certificates of analysis available upon request. We source from reputable manufacturers and verify purity through independent analysis. Our product is ≥98% pure, suitable for research applications .

Authentic & Verified Compounds
Every batch of our 5-MAPB is accompanied by detailed product specifications, ensuring you receive the exact compound you ordered. The correct CAS number is 1823925-53-6 .

Secure Checkout Experience
Our platform features secure checkout with multiple payment options, protecting your information throughout the transaction.

Discreet USA & Canada Delivery
We prioritize your privacy with discreet shipping and camouflage packaging for all orders. Fast shipping is available to all 50 states and Canadian provinces.

Competitive Pricing & Bulk Discounts
Whether you need a single unit or wholesale quantities, our pricing structure rewards larger orders. Buy 5-MAPB in bulk and save on your research chemical needs.

Excellent Customer Support
Our knowledgeable team understands the technical requirements of research chemicals and is available to assist with your questions.

H3: Buy 5-MAPB Cheap and Safe Colorado

When you buy 5-MAPB cheap and safe Colorado, Colorado Shroom Store is your trusted local source for premium research chemicals. We understand that researchers need reliable access to quality compounds at competitive prices. Our Colorado-based operations allow us to provide:

• Competitive pricing without compromising quality

• Fast shipping to all Colorado locations

• Local customer support in your time zone

• Secure transactions with multiple payment options

• Discreet packaging delivered directly to your laboratory or research facility

The Importance of Buying 5-MAPB from a Trusted Source

Purchasing 5-MAPB from a reputable supplier is of paramount importance for several reasons:

1. Product Integrity and Purity
5-MAPB is a synthetic benzofuran that requires careful synthesis and purification. The presence of impurities or incorrect isomers can compromise research results. 5-MAPB’s pharmacological profile differs measurably from its close analogs 5-APB, 6-MAPB, and MDMA across multiple independent assay dimensions . Our lab-tested 5-MAPB is verified to ≥98% purity, ensuring accurate and reproducible experimental outcomes.

2. Regulatory Compliance
5-MAPB is a controlled substance in numerous jurisdictions worldwide . Benzofurans were permanently banned as Class B substances in the U.K. in 2014 . Purchasing from a legitimate supplier ensures compliance with applicable regulations.

3. Forensic and Research Legitimacy
For forensic and analytical research, traceability and documentation are essential. Our 5-MAPB is supplied with Certificates of Analysis confirming identity and purity, meeting the requirements of analytical laboratories. Validated LC-MS/MS and GC-MS methods are essential for detection in biological matrices .

4. Safety Considerations
5-MAPB has been associated with significant effects in scientific studies. Research demonstrates that 5-MAPB has a higher risk of lethal intoxication than MDMA . A fatal co-intoxication case involving 5-MAPB has been reported with a postmortem blood concentration of 101 ng/mL . These findings underscore the importance of handling 5-MAPB only in controlled laboratory settings with appropriate safety protocols.

Explore Our 5-MAPB Selection

Our 5-MAPB research chemical is available in a high purity crystalline powder form. When you buy 5-MAPB USA, you receive:

Product Specifications

• Chemical Name: N,α-dimethyl-5-benzofuranethanamine, monohydrochloride / 5-(2-Methylaminopropyl)benzofuran

• CAS Number: 1823925-53-6

• Molecular Formula: C₁₂H₁₅NO·HCl

• Molecular Weight: 225.7 g/mol

• Appearance: White to off-white crystalline solid

• Purity: ≥98% (lab-tested)

• Solubility: DMF: 25 mg/ml, DMSO: 25 mg/ml, Ethanol: 10 mg/ml, PBS (pH 7.2): 10 mg/ml

• λmax: 246, 279, 286 nm

• Storage: Store at -20°C, protect from light

• Shipping: Room temperature in continental US

Available Quantities

• Single-unit purchases for individual researchers (1 mg, 5 mg, 10 mg)

• Bulk quantities for laboratories and institutions

• Wholesale pricing for commercial research organizations

 How to Store Research Chemicals Correctly

Proper chemical storage is essential for maintaining compound integrity, ensuring safety, and maximizing efficiency in the laboratory. Good chemical and sample management helps you avoid repeating experiments, save costs, and avoid costly waste disposal of expired chemicals.

General Storage Guidelines:

Containers

• Chemicals must be stored in containers made of material compatible with the chemical

• Containers must be in good condition with no signs of cracks or corrosion

• Containers must have lids that can be closed tightly to prevent evaporation and leakage, even if the container falls over

• Ensure all containers are clearly labeled with the chemical’s full name, CAS number, owner’s name, date of receipt, and any necessary hazard information

Segregation by Compatibility

• Incompatible chemical classes must be segregated by cabinets, distance, and/or secondary containment

• Separate acids from bases, cyanides, azides, bleach, sulfides, and metals

• Store oxidizers away from organics and reducing agents

• Store organics and inorganics separately

• Separate pyrophoric materials from flammables

• Do not store chemicals alphabetically – always store by compatibility

Temperature Control

• Many research chemicals require cold storage at -20°C to preserve stability

• For compounds like 5-MAPB, storage at -20°C with protection from light is recommended

• Do not store flammable liquids or volatile hazardous chemicals in cold or warm rooms

• Flammable-material storage refrigerators are mandatory for cold storage of flammable chemicals

Recommended Storage Conditions for 5-MAPB:

Best Practices:

• Store chemicals on sturdy, level shelving with liquid chemicals not stored above eye level

• Do not store chemicals on the floor unless in secondary containment

• Return chemicals to their designated storage promptly after use

• Schedule regular inventories and remove expired chemicals

• If incompatible materials must be stored in the same cabinet, provide secondary containment and segregation

• Use desiccators for chemicals that react with air or water or are hygroscopic

 Bulk Orders – Wholesale 5-MAPB for Research Institutions

For research institutions, contract research organizations, and commercial laboratories, Colorado Shroom Store offers bulk 5-MAPB at competitive wholesale prices. Buy 5-MAPB in bulk and enjoy significant savings on large orders.

Benefits of Bulk Ordering:

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Contact our team to discuss your 5-MAPB wholesale requirements and receive a customized quote.

Delivery Information – USA & Canada Shipping

Colorado Shroom Store is committed to providing reliable, discreet shipping for all research chemical orders. When you buy 5-MAPB online from us, you can expect:

USA Delivery

• Fast shipping to all 50 states

• Tracking number provided for all orders

• Discreet packaging ensuring your privacy

• Overnight delivery options available for urgent research needs

• Room temperature shipping in continental US

Canada Delivery

• Secure delivery to all Canadian provinces

• Compliance with Canadian import regulations

• Camouflage packaging for discretion

• Real-time tracking information

• Fast shipping to major Canadian cities

Shipping Security

• Vacuum-sealed and odor-proof packaging

• Insurance options for shipment protection

• Signature confirmation for high-value orders

 Why Customers Choose Colorado Shroom Store

Our customers consistently choose Colorado Shroom Store for their research chemical needs because we deliver on our promises of quality, reliability, and service.

Trust & Reliability

• Years of experience in the research chemical industry

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Customer-Centric Service

• Knowledgeable support team with technical expertise

• Responsive customer service during business hours

• Commitment to customer satisfaction

Shopping Experience

• Easy online ordering with secure checkout

• Transparent product specifications and pricing

• Comprehensive product information to inform purchasing decisions

Frequently Asked Questions (FAQs)

Q: What is 5-MAPB (5-(2-Methylaminopropyl)benzofuran)?
A: 5-MAPB is a synthetic substituted benzofuran belonging to the aminoalkylbenzofuran class of entactogenic compounds. It is structurally and pharmacologically related to MDMA and is used for research purposes.

Q: What is the CAS number for 5-MAPB?
A: The CAS number for 5-MAPB hydrochloride is 1823925-53-6.

Q: What is the purity of your 5-MAPB?
A: Our 5-MAPB is lab-tested and meets rigorous quality standards with ≥98% purity. Certificate of analysis is available upon request.

Q: How should I store 5-MAPB?
A: Store in a well-closed container at -20°C in a cool, dry place, protected from light and moisture.

Q: What are the physical properties of 5-MAPB?
A: 5-MAPB has a molecular formula of C₁₂H₁₅NO·HCl and a molecular weight of 225.7 g/mol. It appears as a white to off-white crystalline solid with λmax at 246, 279, and 286 nm.

Q: What is the mechanism of action of 5-MAPB?
A: 5-MAPB acts as a substrate-type releaser at serotonin (SERT), norepinephrine (NET), and dopamine (DAT) transporters with nanomolar potencies. It is approximately 3-fold more potent than MDMA at these transporters.

Q: What are the research applications of 5-MAPB?
A: 5-MAPB is used in monoamine transporter release studies, analytical method development, forensic and toxicological research, and structure-activity relationship investigations.

Q: What payment methods do you accept?
A: We offer multiple secure checkout options. Buy 5-MAPB with credit card or choose from other secure payment methods.

Q: Do you offer USA delivery?
A: Yes, we provide reliable USA delivery to all 50 states with fast shipping options.

Q: Do you offer Canada delivery?
A: Yes, we provide dependable Canada delivery with tracking and discreet packaging.

Q: Can I buy 5-MAPB in bulk?
A: Yes, we offer bulk sales and wholesale pricing for qualified buyers. Buy 5-MAPB in bulk and save. Contact us for a quote.

Q: Is your shipping discreet?
A: Yes, we use discreet packaging and camouflage methods to ensure your privacy. We offer fast shipping with tracking for all orders.

Q: Do you offer overnight shipping?
A: Yes, overnight shipping is available for qualifying orders. Buy 5-MAPB with fast shipping and receive your order quickly.

Q: What is the legal status of 5-MAPB?
A: 5-MAPB is a controlled substance in numerous jurisdictions worldwide. Benzofurans were permanently banned as Class B substances in the U.K. in 2014. Please ensure compliance with all applicable laws in your jurisdiction.

Q: How does 5-MAPB differ from 5-APB?
A: 5-MAPB is the N-methylated version of 5-APB. Unlike 5-APB, which displays broad 5-HT2A/B/C agonist activity, 5-MAPB’s 5-HT2 receptor agonism is restricted to the 5-HT2C subtype.

Q: How does 5-MAPB compare to MDMA?
A: 5-MAPB is approximately 3-fold more potent than MDMA at monoamine transporters and produces a substantially larger hyperthermic response with higher lethality risk in murine models at equivalent molar doses.

Q: What are the metabolites of 5-MAPB?
A: The main metabolites are 5-APB (N-demethyl metabolite) and 3-carboxymethyl-4-hydroxy methamphetamine. CYP2B6 is the primary enzyme responsible for 5-MAPB N-demethylation.

Q: Is a Certificate of Analysis (COA) provided with my order?
A: Yes, every order comes with a Certificate of Analysis confirming the identity and purity of the product.

Q: Can I use 5-MAPB for human consumption?
A: No. This product is intended for research and laboratory applications only. It is not for human or veterinary use.

Q: What analytical methods are used to detect 5-MAPB?
A: LC-MS/MS and GC-MS are commonly used for the detection and quantification of 5-MAPB in biological matrices. UHPLC/MS-MS has been used for quantification in forensic cases